Description

1-(Cyclopropylcarbonyl)-1,2,3,4-Tetrahydroquinolin-7-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused quinoline and cyclopropane structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs, particularly for central nervous system (CNS) and oncological targets.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates, especially those targeting neurological disorders.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular architectures via further functionalization of the amine and carbonyl groups.
• Chemical Research & Development: Serves as a reference standard and a starting material in academic and industrial R&D labs for studying structure-activity relationships (SAR).
• API Development: Integral to the synthesis pathway of potential Active Pharmaceutical Ingredients (APIs) in preclinical and clinical development stages.
• Ligand Synthesis: Can be utilized in the preparation of specialized ligands for catalysis or biochemical assays.

Basic Information

Product Name	1-(Cyclopropylcarbonyl)-1,2,3,4-Tetrahydroquinolin-7-Amine
CAS No.	927996-40-5
Molecular Formula	C13H16N2O
Molecular Weight	216.28 g/mol
Synonyms	7-Amino-1-(cyclopropylcarbonyl)-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-7-quinolinamine, 1-(cyclopropylcarbonyl)-; 1-(Cyclopropanecarbonyl)-1,2,3,4-tetrahydroquinolin-7-amine; 7-Amino-1-(cyclopropanecarbonyl)-1,2,3,4-tetrahydroquinoline; 1-(Cyclopropylcarbonyl)-7-amino-1,2,3,4-tetrahydroquinoline; CAS 927996-40-5
EINECS	Contact for details

Quality Control

Our 1-(Cyclopropylcarbonyl)-1,2,3,4-Tetrahydroquinolin-7-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.