Description

[Methyl-(2-Trifluoromethyl-Quinazolin-4-Yl)-Amino]-Acetic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinazoline core functionalized with a trifluoromethyl group. This compound matters for its critical role in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. Pharmaceutical companies, agrochemical R&D laboratories, and academic institutions engaged in drug discovery for oncology, CNS disorders, and other therapeutic areas are the primary users of this specialized building block.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its privileged quinazoline scaffold.
• Agrochemical Development: Serves as a building block for novel active ingredients in crop protection products.
• Chemical Biology Probes: Utilized in the design and synthesis of chemical probes for studying biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of complex molecules for clinical trials.
• Academic & Institutional R&D: Employed in university and research institute laboratories for exploratory synthetic projects.

Basic Information

Product Name	[Methyl-(2-Trifluoromethyl-Quinazolin-4-Yl)-Amino]-Acetic Acid
CAS No.	927969-23-1
Molecular Formula	C₁₂H₁₀F₃N₃O₂
Molecular Weight	285.22 g/mol
Synonyms	N-Methyl-N-(2-trifluoromethylquinazolin-4-yl)glycine; (Methyl(2-(trifluoromethyl)quinazolin-4-yl)amino)acetic acid; 2-[(Methyl)[2-(trifluoromethyl)quinazolin-4-yl]amino]acetic acid; Glycine, N-methyl-N-(2-(trifluoromethyl)-4-quinazolinyl)-; 927969-23-1; Methyl(2-trifluoromethylquinazolin-4-yl)aminoacetic acid; 4-Quinazolineacetic acid, α-[(methyl)[2-(trifluoromethyl)-4-quinazolinyl]amino]-
EINECS	Contact for details

Quality Control

Our [Methyl-(2-Trifluoromethyl-Quinazolin-4-Yl)-Amino]-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.