Description

4-(4-Hydroxypiperidin-1-Yl)-2-Methylquinoline is a high-purity, advanced pharmaceutical intermediate with the CAS number 927801-80-7. This heterocyclic compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing quinoline and piperidine-based molecular scaffolds.
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial laboratories for method development and biological activity studies.
• API Process Development: Employed in scaling up and optimizing synthetic routes for potential new chemical entities (NCEs).
• Chemical Reference Standard: Used for analytical method validation, quality control, and regulatory submissions.

Basic Information

Product Name	4-(4-Hydroxypiperidin-1-Yl)-2-Methylquinoline
CAS No.	927801-80-7
Molecular Formula	C15H18N2O
Molecular Weight	242.32 g/mol
Synonyms	2-Methyl-4-(4-hydroxypiperidin-1-yl)quinoline; 4-(4-Hydroxy-1-piperidinyl)-2-methylquinoline; 1-(2-Methylquinolin-4-yl)piperidin-4-ol; 927801-80-7; 4-(4-Hydroxypiperidino)-2-methylquinoline; 2-Methyl-4-(4-piperidinol-1-yl)quinoline
EINECS	Contact for details

Quality Control

Our 4-(4-Hydroxypiperidin-1-Yl)-2-Methylquinoline is manufactured under strict quality management systems. Every batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.