Description

2-Propyl-6-Trifluoromethoxyquinolin-4-Ol is a specialized fluorinated quinoline derivative, a high-value intermediate in advanced organic synthesis. Its molecular structure, featuring a trifluoromethoxy group and a hydroxyl substituent, makes it a critical building block for creating compounds with enhanced biological activity and metabolic stability. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on developing new active ingredients with improved efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in therapeutic areas targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Serves as a precursor in the synthesis of advanced pesticides and herbicides, where the fluorine atoms contribute to lipophilicity and environmental persistence.
• Material Science: Used in the research of organic electronic materials and liquid crystals, where its rigid quinoline core and fluorine content can influence electronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent tags or molecular probes for studying biological processes.
• Catalyst Ligand Synthesis: Potential building block for creating novel ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	2-Propyl-6-Trifluoromethoxyquinolin-4-Ol
CAS No.	927800-83-7
Molecular Formula	C₁₄H₁₄F₃NO₂
Molecular Weight	285.26 g/mol
Synonyms	4-Hydroxy-2-propyl-6-(trifluoromethoxy)quinoline; 6-(Trifluoromethoxy)-2-propylquinolin-4-ol; 2-Propyl-6-trifluoromethoxy-4-quinolinol; 4-Quinolinol, 2-propyl-6-(trifluoromethoxy)-; 2-n-Propyl-6-trifluoromethoxy-4-hydroxyquinoline
EINECS	Contact for details

Quality Control

Every batch of 2-Propyl-6-Trifluoromethoxyquinolin-4-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive R&D and scale-up processes. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), identity (IR, NMR), and impurity profile is supplied with each shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.