Description

8-Bromo-4-Hydroxy-2-Phenylquinoline is a versatile brominated quinoline derivative that serves as a critical synthetic intermediate and building block in advanced organic chemistry. Its unique structure, featuring both a bromine substituent and a phenolic hydroxyl group, makes it a valuable precursor for constructing complex heterocyclic systems and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobial agents, and other bioactive quinoline-based molecules.
• Agrochemical Research: Used in the creation of new herbicides, fungicides, and pesticides, leveraging the quinoline scaffold's biological activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transporting or emissive layer materials in electronic display and lighting technologies.
• Coordination Chemistry & Catalysis: Acts as a ligand for metal complexes used in catalytic processes and the development of functional materials.
• Dye & Pigment Synthesis: Intermediate in the production of specialized quinoline-based dyes and colorants.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis, including cross-coupling reactions and heterocycle formation.

Basic Information

Product Name	8-Bromo-4-Hydroxy-2-Phenylquinoline
CAS No.	927800-73-5
Molecular Formula	C15H10BrNO
Molecular Weight	300.15 g/mol
Synonyms	8-Bromo-2-phenyl-4-quinolinol; 4-Hydroxy-8-bromo-2-phenylquinoline; 2-Phenyl-8-bromoquinolin-4-ol; 8-Bromo-4-hydroxy-2-phenylquinoline; 8-Bromo-2-phenylquinolin-4-ol; 4-Quinolinol, 8-bromo-2-phenyl-; 927800-73-5
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Hydroxy-2-Phenylquinoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters. We are committed to meeting the stringent requirements of research and development as well as scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to handle the material under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.