Description

4-Chloro-2-Methyl-8-Trifluoromethoxyquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated quinoline structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical manufacturers and R&D laboratories focused on developing new therapeutic agents, especially in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a precursor for the synthesis of specialized organic ligands and functional materials.
• Academic & Industrial R&D: Essential for chemical research exploring structure-activity relationships (SAR) and new synthetic methodologies.
• Fluorinated Compound Synthesis: The trifluoromethoxy group makes it a valuable synthon for introducing fluorine into target molecules to modulate their properties.

Basic Information

Product Name	4-Chloro-2-Methyl-8-Trifluoromethoxyquinoline
CAS No.	927800-56-4
Molecular Formula	C12H7ClF3NO
Molecular Weight	273.64 g/mol
Synonyms	8-Trifluoromethoxy-4-chloro-2-methylquinoline; 4-Chloro-2-methyl-8-(trifluoromethoxy)quinoline; 2-Methyl-4-chloro-8-trifluoromethoxyquinoline; Quinoline, 4-chloro-2-methyl-8-(trifluoromethoxy)-; 927800-56-4; 4-Chloro-2-methyl-8-trifluoromethoxy-quinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methyl-8-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong alkalis and fluorides. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.