Description

Dichloro[1,3-Bis(2-Methylphenyl)-2-Imidazolidinylidene](Benzylidene)(Tricyclohexylphosphine)Ruthenium(II) is a highly specialized, second-generation Grubbs-Hoveyda type olefin metathesis catalyst. This compound is valued for its exceptional thermal stability and functional group tolerance, enabling complex synthetic transformations under mild conditions. It is a critical reagent for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, facilitating the efficient construction of carbon-carbon double bonds in target molecules.

Application

• Pharmaceutical Intermediate Synthesis: Key catalyst for ring-closing metathesis (RCM), cross metathesis (CM), and ring-opening metathesis polymerization (ROMP) in the production of active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring complex olefin architectures.
• Polymer & Material Science: Enables the creation of specialty polymers, functionalized surfaces, and self-healing materials via controlled ROMP reactions.
• Fine Chemical & Fragrance Manufacturing: Facilitates the efficient and selective synthesis of olefinic compounds used in flavors, fragrances, and specialty chemicals.
• Academic & Industrial R&D: An essential tool for methodological development in organic synthesis and catalysis research.
• Process Chemistry Optimization: Employed for scaling up metathesis reactions due to its robustness and ease of handling compared to earlier catalyst generations.

Basic Information

Product Name	Dichloro[1,3-Bis(2-Methylphenyl)-2-Imidazolidinylidene](Benzylidene)(Tricyclohexylphosphine)Ruthenium(II)
CAS No.	927429-60-5
Molecular Formula	C46H60Cl2N2PRu
Molecular Weight	848.90 g/mol
Synonyms	Grubbs-Hoveyda Catalyst 2nd Generation; Hoveyda-Grubbs Catalyst 2nd Gen; Dichloro(o-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium(II) (with NHC ligand); (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium(II) (common structural analog name); HG-II Catalyst; Zhan Catalyst 1B; Ru-based Olefin Metathesis Catalyst; [RuCl2(=CH-2-(2-PrO)-C6H4)(IMesH2)(PCy3)]
EINECS	Contact for details

Quality Control

Every batch of our ruthenium metathesis catalysts is synthesized and handled under stringent inert atmosphere conditions to ensure optimal activity and shelf life. Our products undergo rigorous quality testing to ensure compliance with industry standards. Identity and purity are confirmed via advanced analytical techniques including NMR (1H, 13C, 31P) and HPLC. Certificates of Analysis (COA) detailing batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. The product is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Purple to brown crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Solubility	Soluble in common organic solvents (DCM, toluene, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.