Description

8-(Bromomethyl)-6-Fluoroquinoline is a high-value, multi-functional halogenated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and a fluorine atom, makes it an indispensable precursor for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical developers engaged in medicinal chemistry, agrochemical research, and materials science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel fluoroquinolone-based antibiotics and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of new-generation fungicides and herbicides that leverage the quinoline scaffold.
• Material Science Research: Serves as a monomer or functionalizing agent for creating specialized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes due to the inherent photophysical properties of the quinoline core.
• Cross-Coupling Reactions: The bromomethyl group acts as an excellent handle for further functionalization via Suzuki, Heck, or other palladium-catalyzed cross-coupling reactions.
• Ligand Preparation: Intermediate for synthesizing complex chelating ligands used in catalysis and metal coordination chemistry.

Basic Information

Product Name	8-(Bromomethyl)-6-Fluoroquinoline
CAS No.	926262-79-5
Molecular Formula	C11H7BrFN
Molecular Weight	252.08 g/mol
Synonyms	6-Fluoro-8-(bromomethyl)quinoline; 8-Bromomethyl-6-fluoroquinoline; Quinoline, 8-(bromomethyl)-6-fluoro-; 6-Fluoro-8-quinolinemethyl bromide
EINECS	Contact for details

Quality Control

Every batch of 8-(Bromomethyl)-6-Fluoroquinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.