Description

6,8-Difluoro-1,2,3,4-Tetrahydroquinoline is a fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a privileged intermediate for constructing complex pharmacophores. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of fluorine atoms.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, dyes, and liquid crystals.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and as a scaffold for designing molecular probes and drug candidates.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated quinoline derivatives.

Basic Information

Product Name	6,8-Difluoro-1,2,3,4-Tetrahydroquinoline
CAS No.	926218-72-6
Molecular Formula	C9H7F2N
Molecular Weight	167.16 g/mol
Synonyms	6,8-Difluoro-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-6,8-difluoroquinoline; 6,8-Difluoro-3,4-dihydro-2H-quinoline; 6,8-Difluoro-1,2,3,4-tetrahydro-quinoline; 6,8-Difluoro THQ; 6,8-F2-THQ
EINECS	Contact for details

Quality Control

Our 6,8-Difluoro-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.