Description

2-Bromo-4-Fluoro-5-(Chlorosulfonyl)Benzoic Acid is a high-value, multi-functional aromatic building block used in advanced organic synthesis. Its unique structure, featuring bromo, fluoro, and chlorosulfonyl substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated benzoic acid core.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and other specialty materials requiring sulfonyl chloride reactivity.
• Chemical Derivatization: The reactive chlorosulfonyl group allows for facile conversion into various sulfonamides, sulfonate esters, and sulfonic acids for diverse applications.
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CROs/CMOs developing proprietary compounds for clients.

Basic Information

Product Name	2-Bromo-4-Fluoro-5-(Chlorosulfonyl)Benzoic Acid
CAS No.	926195-99-5
Molecular Formula	C7H3BrClFO4S
Molecular Weight	317.52 g/mol
Synonyms	5-(Chlorosulfonyl)-2-bromo-4-fluorobenzoic acid; Benzoic acid, 2-bromo-4-fluoro-5-(chlorosulfonyl)-; 2-Bromo-4-fluoro-5-sulfonylchloride benzoic acid; 926195-99-5; 2-Br-4-F-5-SO2Cl-BA
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-5-(Chlorosulfonyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under dry conditions. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.