Description

(S)-3-Amino-2-Methylpropanoic Acid-Hcl CAS NO 925704-45-6 is a high-purity, non-proteinogenic amino acid derivative with a defined stereochemistry, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a stereochemically pure scaffold for constructing complex molecules, ensuring the final product's desired biological activity and pharmacological profile. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel active pharmaceutical ingredients (APIs), peptide mimetics, and diagnostic agents.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, especially in oncology and neurology.
• Peptide Chemistry: Used in solid-phase peptide synthesis (SPPS) to incorporate a sterically hindered, β-branched amino acid residue into peptide chains.
• Protease Inhibitor Development: Serves as a core structural component in designing selective enzyme inhibitors.
• Bioconjugation & Labeling: The primary amine functionality allows for conjugation with fluorescent dyes, biotin, or other reporter molecules for diagnostic applications.
• Chemical Biology Research: Employed in studying enzyme mechanisms and protein-protein interactions using synthetic analogs.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in catalytic asymmetric transformations.

Basic Information

Product Name	(S)-3-Amino-2-Methylpropanoic Acid Hydrochloride
CAS No.	925704-45-6
Molecular Formula	C4H9NO2 • HCl
Molecular Weight	139.58 g/mol
Synonyms	(S)-3-Amino-2-methylpropionic acid hydrochloride; (S)-2-Methyl-β-alanine hydrochloride; D-2-Methyl-β-alanine hydrochloride; (S)-3-Amino-2-methylpropanoic acid HCl; (2S)-3-Amino-2-methylpropanoic acid hydrochloride; (S)-2-Aminoisobutyric acid β-isomer hydrochloride; 3-Amino-2-(S)-methylpropionic acid hydrochloride; H-β-Aib(Me)-OH • HCl
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-2-Methylpropanoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.