Description

7-Bromo-5-Fluoro-1,2,3,4-Tetrahydronaphthalen-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated tetrahydronaphthalenone structure. This compound is a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex molecules for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses, including cross-coupling reactions and functional group transformations, due to its reactive bromo and keto groups.
• Agrochemical Research: Acts as a starting material for developing new active ingredients with potential herbicidal or pesticidal properties.
• Material Science: Investigated for the creation of specialty chemicals and advanced organic materials requiring specific halogenated aromatic frameworks.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) settings for methodological studies and the exploration of new chemical entities.

Basic Information

Item	Details
Product Name	7-Bromo-5-Fluoro-1,2,3,4-Tetrahydronaphthalen-1-One
CAS No.	925442-95-1
Molecular Formula	C10H8BrFO
Molecular Weight	243.07 g/mol
Synonyms	7-Bromo-5-fluoro-3,4-dihydro-1(2H)-naphthalenone; 7-Bromo-5-fluoro-1-tetralone; 7-Bromo-5-fluoro-3,4-dihydronaphthalen-1(2H)-one; 1(2H)-Naphthalenone, 7-bromo-5-fluoro-3,4-dihydro-; 7-Br-5-F-1-tetralone; 925442-95-1; 7-Bromo-5-fluoro-α-tetralone
EINECS	Contact for details

Quality Control

Our 7-Bromo-5-Fluoro-1,2,3,4-Tetrahydronaphthalen-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.