Description

3-[(1R)-2-Chloro-1-Hydroxyethyl]Phenol is a chiral phenolic intermediate of significant importance in asymmetric synthesis. This compound matters for its role as a key building block in the production of high-value, optically active pharmaceuticals and fine chemicals. Pharmaceutical R&D teams and fine chemical manufacturers need it for developing active pharmaceutical ingredients (APIs), particularly those targeting adrenergic receptors and central nervous system disorders.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of β-blockers and other cardiovascular drugs.
• Asymmetric Synthesis: Used as a starting material or resolving agent for creating enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for developing novel, chiral active ingredients for crop protection.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for metal-catalyzed reactions.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals requiring specific stereochemistry.
• Academic and R&D Laboratories: Used in research focused on organic methodology and medicinal chemistry.

Basic Information

Product Name	3-[(1R)-2-Chloro-1-Hydroxyethyl]Phenol
CAS No.	925430-39-3
Molecular Formula	C8H9ClO2
Molecular Weight	172.61 g/mol
Synonyms	(R)-1-(3-Hydroxyphenyl)-2-chloroethanol; (1R)-1-(3-Hydroxyphenyl)-2-chloroethan-1-ol; (R)-3-(2-Chloro-1-hydroxyethyl)phenol; 3-[(R)-2-Chloro-1-hydroxyethyl]phenol; (R)-M-Chlorophenylethylene Glycol; (R)-3-Hydroxy-α-(chloromethyl)benzyl Alcohol; (R)-3-(2-Chloro-1-hydroxyethyl)phenol; 925430-39-3
EINECS	Contact for details

Quality Control

Our 3-[(1R)-2-Chloro-1-Hydroxyethyl]Phenol is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical R&D and advanced synthesis. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles. Certificates are available upon request to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.