Description

2,2,4,6-Tetramethyl-1,2-Dihydroquinoline-8-Carboxylic Acid is a specialized, high-purity organic compound belonging to the substituted quinoline class. This chemical serves as a critical advanced intermediate for the synthesis of complex molecules, offering unique steric and electronic properties due to its tetramethyl-substituted dihydroquinoline core. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active ingredients and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its complex heterocyclic structure.
• Material Science Research: Acts as a precursor or additive in the development of specialty polymers, dyes, and organic electronic materials.
• Catalyst Ligand Synthesis: Employed to create sophisticated ligands for transition metal catalysis in asymmetric synthesis.
• Academic & Industrial R&D: Serves as a valuable reagent for chemical research in universities and corporate laboratories.
• Fine Chemical Production: An intermediate for manufacturing other high-value, complex organic compounds.

Basic Information

Product Name	2,2,4,6-Tetramethyl-1,2-Dihydroquinoline-8-Carboxylic Acid
CAS No.	925192-36-5
Molecular Formula	C₁₄H₁₇NO₂
Molecular Weight	231.29 g/mol
Synonyms	8-Carboxy-2,2,4,6-tetramethyl-1,2-dihydroquinoline; 2,2,4,6-Tetramethyl-1,2-dihydroquinoline-8-carboxylic acid; TMQ-8-COOH; 1,2-Dihydro-2,2,4,6-tetramethylquinoline-8-carboxylic acid; 8-Quinolinecarboxylic acid, 1,2-dihydro-2,2,4,6-tetramethyl-; Tetramethyl dihydroquinoline carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 2,2,4,6-Tetramethyl-1,2-Dihydroquinoline-8-Carboxylic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Quality is verified through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We operate under a cGMP-compliant quality management system suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.