Description

4-(2-(6-Methylpyridin-2-Yl)-5,6-Dihydro-4H-Pyrrolo[1,2-B]Pyrazol-3-Yl)Quinoline-6-Carbonitrile is a sophisticated heterocyclic organic compound with a complex fused-ring structure, serving as a critical advanced pharmaceutical intermediate and key building block in modern synthetic chemistry. Its unique molecular architecture makes it highly valuable for the research and development of novel bioactive molecules, particularly in the field of kinase inhibitor discovery. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for targeted cancer therapies.
• Kinase Inhibitor Research: Serves as a core scaffold for the development of novel kinase inhibitors due to its privileged heterocyclic structure.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Chemical Biology Probes: Employed in the creation of tool compounds for studying specific biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and methodology development.

Basic Information

Product Name	4-(2-(6-Methylpyridin-2-Yl)-5,6-Dihydro-4H-Pyrrolo[1,2-B]Pyrazol-3-Yl)Quinoline-6-Carbonitrile
CAS No.	924898-13-5
Molecular Formula	C23H17N5
Molecular Weight	363.42 g/mol
Synonyms	4-[2-(6-Methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarbonitrile; 6-Cyano-4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline; Quinoline-6-carbonitrile, 4-[2-(6-methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-; CAS 924898-13-5
EINECS	Contact for details

Quality Control

Our 4-(2-(6-Methylpyridin-2-Yl)-5,6-Dihydro-4H-Pyrrolo[1,2-B]Pyrazol-3-Yl)Quinoline-6-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive (store away from light). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.