Description

Benzoic Acid, 4-[(1S)-1-Hydrazinylethyl]- is a specialized chiral derivative of benzoic acid, featuring a hydrazinyl functional group that makes it a valuable building block in organic synthesis. This compound is critical for the development of high-value, optically active molecules, particularly in the pharmaceutical sector. It is primarily sought by research chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs), chiral ligands, and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Catalyst and Ligand Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic and Industrial Research: A valuable reagent for methodological development in organic chemistry, particularly in hydrazone and hydrazide formation reactions.

Basic Information

Product Name	Benzoic Acid, 4-[(1S)-1-Hydrazinylethyl]-
CAS No.	924887-08-1
Molecular Formula	C9H12N2O2
Molecular Weight	180.21 g/mol
Synonyms	(S)-4-(1-Hydrazinylethyl)benzoic acid; 4-[(1S)-1-Hydrazinylethyl]benzoic acid; p-[(S)-1-Hydrazinylethyl]benzoic acid; (S)-1-(4-Carboxyphenyl)ethylhydrazine; Benzoic acid, 4-[(1S)-1-hydrazinylethyl]-; (S)-HPEBA; (1S)-1-(4-Carboxyphenyl)ethan-1-amine hydrazone
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-[(1S)-1-Hydrazinylethyl]- is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider using an inert atmosphere (e.g., nitrogen or argon) to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.