Description

2H-Benzo[A]Quinolizin-2-Ol, 1,3,4,6,7,11B-Hexahydro-9,10-Dimethoxy-3-(2-Methylpropyl)-, (2R,3S,11Bs)- is a complex, stereochemically defined alkaloid derivative with a benzoquinolizine core structure. This compound is of significant interest for its potential as a key chiral intermediate or pharmacophore in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) or anti-infective research.
• Asymmetric Synthesis: Used as a sophisticated starting material or ligand precursor in catalytic asymmetric reactions due to its defined stereocenters.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs targeting complex alkaloid-like structures.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in regulatory filings.
• Agrochemical Development: Potential application as an intermediate in the synthesis of advanced crop protection agents with specific biological activity.
• Academic Research: Used in universities and research institutes for studying alkaloid chemistry, total synthesis, and novel heterocyclic compound properties.

Basic Information

Product Name	2H-Benzo[A]Quinolizin-2-Ol, 1,3,4,6,7,11B-Hexahydro-9,10-Dimethoxy-3-(2-Methylpropyl)-, (2R,3S,11Bs)-
CAS No.	924854-62-6
Molecular Formula	C19H29NO3
Molecular Weight	319.44 g/mol
Synonyms	(2R,3S,11bS)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-isobutyl-2H-benzo[a]quinolizin-2-ol; 3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizin-2-ol (2R,3S,11bS)-; (2R,3S,11bS)-3-(2-Methylpropyl)-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizin-2-ol; Benzo[a]quinolizine-2-ol derivative; Alkaloid intermediate 924854-62-6
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization using techniques such as HPLC, GC, NMR, and chiral analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.