Description

3-(4-Chlorophenyl)-1,4-Diazaspiro[4.5]Dec-3-En-2-One is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological disorders.
• Organic Synthesis Reagent: Used in research laboratories for constructing complex heterocyclic frameworks and spiro compounds.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Preclinical Development: Employed in the scale-up and process optimization for new chemical entities (NCEs) before clinical trials.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control of related pharmaceutical substances.

Basic Information

Product Name	3-(4-Chlorophenyl)-1,4-Diazaspiro[4.5]Dec-3-En-2-One
CAS No.	923975-81-9
Molecular Formula	C15H17ClN2O
Molecular Weight	276.76 g/mol
Synonyms	3-(4-Chlorophenyl)-1,4-diazaspiro[4.5]dec-3-en-2-one; 1,4-Diazaspiro[4.5]dec-3-en-2-one, 3-(4-chlorophenyl)-; 3-(p-Chlorophenyl)-1,4-diazaspiro[4.5]dec-3-en-2-one; CAS 923975-81-9; Spirocyclic Chlorophenyl Diazinone; 4-Chlorophenyl Diazaspiro Decenone; Pharmaceutical Intermediate 923975-81-9
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorophenyl)-1,4-Diazaspiro[4.5]Dec-3-En-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.