Description

5-(Azepan-1-Ylmethyl)Quinolin-8-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining quinoline and azepane moieties. This compound is critical for medicinal chemistry research and the development of novel therapeutic agents, offering a versatile scaffold for targeted drug discovery. It is primarily utilized by R&D laboratories and pharmaceutical manufacturers engaged in synthesizing new chemical entities for potential applications in oncology, neurology, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and protein interactions.
• Organic Synthesis: Acts as a versatile reagent for constructing complex heterocyclic compounds in academic and industrial research settings.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and process development projects.

Basic Information

Product Name	5-(Azepan-1-Ylmethyl)Quinolin-8-Ol
CAS No.	923826-40-8
Molecular Formula	C₁₇H₂₂N₂O
Molecular Weight	270.37 g/mol
Synonyms	8-Hydroxy-5-(azepan-1-ylmethyl)quinoline; 5-[(Azepan-1-yl)methyl]quinolin-8-ol; Quinolin-8-ol, 5-(azepan-1-ylmethyl)-; 923826-40-8; 5-(1-Azepanylmethyl)-8-quinolinol; 5-(Azepan-1-ylmethyl)-8-hydroxyquinoline; 8-Quinolinol, 5-[(hexahydro-1H-azepin-1-yl)methyl]-
EINECS	Contact for details

Quality Control

Our 5-(Azepan-1-Ylmethyl)Quinolin-8-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.