Description

4(3H)-Quinazolinone, 2-Chloro-7-Methoxy-8-Methyl- is a high-purity, synthetically derived quinazolinone derivative, serving as a critical advanced pharmaceutical intermediate. This compound is valued for its precise molecular structure, which is essential for the research and development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes for developing new quinazolinone-based molecules.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: Employed as a versatile scaffold for further functionalization and the creation of more complex heterocyclic libraries.
• Biochemical Research: Investigated for its potential biological activity and interactions with various enzymatic targets in preclinical studies.

Basic Information

Product Name	4(3H)-Quinazolinone, 2-Chloro-7-Methoxy-8-Methyl-
CAS No.	923275-17-6
Molecular Formula	C₁₀H₉ClN₂O₂
Molecular Weight	224.64 g/mol
Synonyms	2-Chloro-7-methoxy-8-methylquinazolin-4(3H)-one; 2-Chloro-7-methoxy-8-methyl-4(3H)-quinazolinone; 8-Methyl-2-chloro-7-methoxy-4(3H)-quinazolinone; 2-Chloro-7-methoxy-8-methyl-3,4-dihydroquinazolin-4-one; Quinazolin-4(3H)-one, 2-chloro-7-methoxy-8-methyl-; 923275-17-6; 2-Chloro-7-methoxy-8-methyl-4-quinazolinol
EINECS	Contact for details

Quality Control

Our 4(3H)-Quinazolinone, 2-Chloro-7-Methoxy-8-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.