Description

Rel-N,N''-[[(1R,3S,4S,6R)-4,6-Bis[(Aminoiminomethyl)Amino]-1,3-Cyclohexanedyil]Bis(Oxy-4,1-Phenylene)]Bisguanidine Tetratrifluoroacetate Salt is a high-purity, non-racemic chiral compound that serves as a critical building block in advanced pharmaceutical research and development. This complex guanidine derivative is valued for its precise stereochemistry and functional groups, which enable its use in synthesizing targeted bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in oncology and neurology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Peptidomimetic Development: Serves as a scaffold for creating peptidomimetics due to its guanidine and aromatic functionalities.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand in catalytic asymmetric reactions to induce stereoselectivity.
• High-Value Fine Chemical Production: Integral in the multi-step synthesis of complex, high-purity active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Rel-N,N''-[[(1R,3S,4S,6R)-4,6-Bis[(Aminoiminomethyl)Amino]-1,3-Cyclohexanedyil]Bis(Oxy-4,1-Phenylene)]Bisguanidine Tetratrifluoroacetate Salt
CAS No.	922732-52-3
Molecular Formula	C₃₀H₃₄F₁₂N₁₄O₁₀
Molecular Weight	1006.66 g/mol
Synonyms	1,3-Cyclohexanebis(oxy-4,1-phenylene)diguanidine tetrakis(trifluoroacetate) salt (rel-(1R,3S,4S,6R)-isomer); 4,4'-(rel-(1R,3S,4S,6R)-4,6-Diamidino-1,3-cyclohexanediylbis(oxy))dibenzamidine tetratrifluoroacetate; BDBPA Tetratrifluoroacetate; CAS 922732-52-3; UNII-9K5N6V7Y1I; rel-4,4'-(4,6-Diamidino-1,3-cyclohexanediylbis(oxy))dibenzamidine tetrakis(2,2,2-trifluoroacetate); (1R,3S,4S,6R)-4,6-Bis[(aminoiminomethyl)amino]-1,3-cyclohexanediyl bis(oxy-4,1-phenylene)diguanidine tetratrifluoroacetate
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to stringent quality management systems. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and Mass Spectrometry to confirm identity, chiral purity, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or with appropriate desiccants after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.