Description

Tetramethylguanidine Acetate is a versatile organic salt derived from the potent superbase tetramethylguanidine. This compound is valued for its dual functionality as a strong, non-nucleophilic organic base and a source of the acetate anion. It serves as a critical reagent and catalyst in advanced organic synthesis, particularly where controlled basicity and specific counterion effects are required. Key industrial applications span pharmaceutical intermediates, agrochemical production, and polymer chemistry.

Application

• Pharmaceutical Synthesis: Employed as a catalyst and base in the production of active pharmaceutical ingredients (APIs), especially for condensation and deprotonation reactions.
• Polymerization Catalyst: Used as an efficient catalyst for the production of polyurethanes, polycarbonates, and other specialty polymers.
• Agrochemical Manufacturing: Acts as a key intermediate and catalyst in the synthesis of herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Facilitates a wide range of reactions including esterifications, amidations, and Knoevenagel condensations under mild conditions.
• Ionic Liquid Precursor: Serves as a starting material for the preparation of task-specific ionic liquids used in green chemistry applications.
• Crosslinking Agent: Utilized in resin and epoxy formulations to enhance curing properties and final material performance.

Basic Information

Product Name	Tetramethylguanidine Acetate
CAS No.	16836-76-3
Molecular Formula	C7H17N3O2
Molecular Weight	175.23 g/mol
Synonyms	1,1,3,3-Tetramethylguanidinium Acetate; TMG Acetate; Tetramethylguanidinium Acetate; N,N,N',N'-Tetramethylguanidinium Acetate; Acetic acid, compd. with 1,1,3,3-tetramethylguanidine (1:1); Guanidine, N,N,N',N'-tetramethyl-, acetate; TMGH OAc
EINECS	240-873-0

Quality Control

Our Tetramethylguanidine Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.