Description

4(3H)-Quinazolinone, 8-(Acetyloxy)-2-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]- is a sophisticated quinazolinone derivative, a class of heterocyclic compounds renowned for their significant biological and pharmacological activity. This compound matters as a high-value chemical intermediate and a key building block in advanced organic synthesis, enabling the development of novel molecular entities. It is primarily needed by pharmaceutical R&D organizations and fine chemical manufacturers focused on creating new therapeutic agents, particularly in oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Biochemical Tool Compound: Used in vitro and in vivo to study specific biological pathways and validate new drug targets.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to construct complex molecules for agrochemical and material science applications.
• Academic Research: Utilized in universities and research institutes for developing new synthetic methodologies and exploring heterocyclic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	4(3H)-Quinazolinone, 8-(Acetyloxy)-2-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]-
CAS No.	922189-24-0
Molecular Formula	C20H18N2O5
Molecular Weight	366.37 g/mol
Synonyms	8-Acetoxy-2-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]quinazolin-4(3H)-one; 2-[(E)-2-(3,5-Dimethoxyphenyl)vinyl]-8-hydroxyquinazolin-4(3H)-one 8-acetate; 8-(Acetyloxy)-2-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-4(3H)-quinazolinone; (E)-8-(Acetyloxy)-2-(2-(3,5-dimethoxyphenyl)vinyl)quinazolin-4(3H)-one; 922189-24-0; Quinazolinone derivative, CAS 922189-24-0
EINECS	Contact for details

Quality Control

Our high-purity 4(3H)-Quinazolinone derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.