Description

Methyl 8-Bromo-4-Methoxyquinoline-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated quinoline core structure. This compound is critical for the synthesis of complex bioactive molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific quinoline-based pharmacophores into their target compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting infectious diseases, oncology, and central nervous system disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Acts as a building block for creating novel quinoline-based fungicides, herbicides, or insecticides.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for advanced material science and chemical biology applications.
• Academic Research: Utilized in university and institutional labs for methodological development and studying heterocyclic chemistry reactions.
• Contract Research & Manufacturing (CRMO): Supplied to service organizations supporting outsourced drug discovery and development projects for global clients.

Basic Information

Item	Details
Product Name	Methyl 8-Bromo-4-Methoxyquinoline-2-Carboxylate
CAS No.	921760-93-2
Molecular Formula	C12H10BrNO3
Molecular Weight	296.12 g/mol
Synonyms	8-Bromo-4-methoxyquinoline-2-carboxylic acid methyl ester; Methyl 8-bromo-4-methoxy-2-quinolinecarboxylate; 2-Quinolinecarboxylic acid, 8-bromo-4-methoxy-, methyl ester; 8-Bromo-4-methoxy-2-quinolinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 8-Bromo-4-Methoxyquinoline-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for your development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.