Description

tert-Butyl6-(5-(Methoxycarbonyl)Pyridin-3-Yl)-4-Oxospiro[Chroman-2,4'-Piperidine]-1'-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and heterocyclic architecture. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of small molecule drugs targeting central nervous system disorders and other complex diseases.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: Used in the research and synthesis of potential inhibitors for various enzymatic targets due to its specific structural motifs.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Item	Details
Product Name	tert-Butyl6-(5-(Methoxycarbonyl)Pyridin-3-Yl)-4-Oxospiro[Chroman-2,4'-Piperidine]-1'-Carboxylate
CAS No.	921760-67-0
Molecular Formula	C26H28N2O6
Molecular Weight	464.51 g/mol
Synonyms	1'-Boc-6-(5-(Methoxycarbonyl)pyridin-3-yl)-4-oxospiro[chroman-2,4'-piperidine]; tert-Butyl 6-(5-(methoxycarbonyl)pyridin-3-yl)-4-oxospiro[chroman-2,4'-piperidine]-1'-carboxylate; 1'-(tert-Butoxycarbonyl)-6-[5-(methoxycarbonyl)-3-pyridyl]spiro[3,9-dihydro-1-benzopyran-2,4'-piperidine]-4-one; Spiro[chroman-2,4'-piperidine]-1'-carboxylic acid, 6-[5-(methoxycarbonyl)-3-pyridinyl]-4-oxo-, 1,1-dimethylethyl ester; 921760-67-0; Boc-protected spirochromone piperidine intermediate
EINECS	Contact for details

Quality Control

Our tert-Butyl6-(5-(Methoxycarbonyl)Pyridin-3-Yl)-4-Oxospiro[Chroman-2,4'-Piperidine]-1'-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP standards for advanced intermediates, and specifications can be aligned with client-specific pharmacopeial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.