Description

6-Bromospiro[Chroman-2,4'-Piperidin]-4-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic structure. This compound is of significant commercial importance for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• CNS Drug Development: Serves as a crucial precursor in the development of potential therapeutics for neurological and psychiatric conditions.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CRMOs) for bespoke synthesis projects.
• Academic Research: Used in university and institutional laboratories for advanced organic synthesis and methodological studies.

Basic Information

Product Name	6-Bromospiro[Chroman-2,4'-Piperidin]-4-One Hydrochloride
CAS No.	921760-46-5
Molecular Formula	C14H15BrClNO2
Molecular Weight	344.63 g/mol
Synonyms	6-Bromospiro[chroman-2,4'-piperidin]-4-one HCl; 6-Bromo-4-oxospiro[chroman-2,4'-piperidine] hydrochloride; 6-Bromo-4-oxospiro[2H-1-benzopyran-2,4'-piperidine] hydrochloride; 6-Bromospiro[chroman-2,4'-piperidin]-4-one hydrochloride; 6-Bromo-4-oxospiro[chromane-2,4'-piperidine] hydrochloride; 6-Bromo-4-oxospiro[chroman-2,4'-piperidine] hydrochloride salt; 6-Bromo-4-oxospiro[chroman-2,4'-piperidine] HCl; 6-Bromo-4-oxospiro[chroman-2,4'-piperidine] monohydrochloride
EINECS	Contact for details

Quality Control

Our 6-Bromospiro[Chroman-2,4'-Piperidin]-4-One Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as identity, purity, and impurity profiles to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.