Description

3,3-Difluorocyclohexanamine Hydrochloride is a high-purity, fluorinated amine salt building block of significant interest in advanced organic synthesis. Its value lies in the strategic incorporation of fluorine atoms and the cyclohexylamine scaffold, which are critical for modulating the physicochemical and biological properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the difluoro motif enhances bioavailability and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced materials with unique surface properties.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Scale-Up: A critical starting material for contract research organizations (CROs) and CDMOs offering custom synthesis services.

Basic Information

Product Name	3,3-Difluorocyclohexanamine Hydrochloride
CAS No.	921602-77-9
Molecular Formula	C6H12ClF2N
Molecular Weight	183.62 g/mol
Synonyms	3,3-Difluorocyclohexanamine HCl; 3,3-Difluorocyclohexylamine Hydrochloride; Cyclohexanamine, 3,3-difluoro-, hydrochloride; 3,3-Difluoro-1-cyclohexanamine hydrochloride; 3,3-Difluorocyclohexan-1-amine hydrochloride; (3,3-Difluorocyclohexyl)amine hydrochloride; 921602-77-9
EINECS	Contact for details

Quality Control

Every batch of 3,3-Difluorocyclohexanamine Hydrochloride is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee consistent quality and traceability for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.