Description

2,2-Difluorocyclopentan-1-Amine Hydrochloride is a high-purity, organofluorine building block essential for modern synthetic chemistry. This compound matters as a key chiral intermediate, enabling the efficient construction of complex molecules with precise stereochemistry. Pharmaceutical researchers and fine chemical manufacturers need it for developing novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the difluorocyclopentyl moiety can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty chemicals with unique properties.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	2,2-Difluorocyclopentan-1-Amine Hydrochloride
CAS No.	921599-70-4
Molecular Formula	C5H10ClF2N
Molecular Weight	157.59 g/mol
Synonyms	2,2-Difluorocyclopentanamine Hydrochloride; 1-Amino-2,2-difluorocyclopentane Hydrochloride; Cyclopentanamine, 2,2-difluoro-, hydrochloride; 2,2-Difluorocyclopentylamine Hydrochloride; 2,2-Difluoro-1-aminocyclopentane HCl; 1-Cyclopentylamine, 2,2-difluoro-, hydrochloride; 921599-70-4; 2,2-Difluorocyclopentan-1-amine HCl
EINECS	Contact for details

Quality Control

Our 2,2-Difluorocyclopentan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.