Description

2-Chloro-8-(Trifluoromethyl) Quinoline is a high-value halogenated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, makes it an essential intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging the bioactivity of the quinoline core.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Utilized to synthesize complex chelating ligands for metal catalysis and coordination chemistry.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial R&D labs.

Basic Information

Product Name	2-Chloro-8-(Trifluoromethyl) Quinoline
CAS No.	920494-31-1
Molecular Formula	C10H5ClF3N
Molecular Weight	231.60 g/mol
Synonyms	8-Trifluoromethyl-2-chloroquinoline; 2-Chloro-8-(trifluoromethyl)quinoline; Quinoline, 2-chloro-8-(trifluoromethyl)-; 2-Chloro-8-trifluoromethylquinoline; 920494-31-1
EINECS	Contact for details

Quality Control

Our 2-Chloro-8-(Trifluoromethyl) Quinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.