Description

2-Methylazetidin-3-Ol Hydrochloride is a high-purity, fine chemical building block of significant interest in advanced organic synthesis. This compound serves as a crucial chiral intermediate, enabling the construction of complex molecular architectures with precise stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other biologically active compounds, particularly for projects requiring constrained azetidine scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) where the azetidine ring system is a core structural motif.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes, enzyme inhibitors, and ligands to study biological pathways and protein function.
• Agrochemical Research: Serves as an intermediate in the discovery and synthesis of novel agrochemicals, such as herbicides and fungicides, with potentially improved efficacy and environmental profiles.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including studies on ring-opening reactions, stereoselective transformations, and catalysis.

Basic Information

Product Name	2-Methylazetidin-3-Ol Hydrochloride
CAS No.	920282-10-6
Molecular Formula	C4H10ClNO
Molecular Weight	123.58 g/mol
Synonyms	3-Hydroxy-2-methylazetidine hydrochloride; 2-Methyl-3-hydroxyazetidine hydrochloride; (±)-2-Methylazetidin-3-ol hydrochloride; Azetidin-3-ol, 2-methyl-, hydrochloride; 3-Azetidinol, 2-methyl-, hydrochloride (1:1); 920282-10-6; 2-Methyl-3-azetidinol hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Methylazetidin-3-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral assay, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.