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Ruthenium, Dichloro(3-Phenyl-1H-Inden-1-Ylidene)Bis(Pyridine)(Tricyclohexylphosphine)-, (Oc-6-13)- CAS NO 920278-29-1
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CAS No.:920278-29-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Ruthenium, Dichloro(3-Phenyl-1H-Inden-1-Ylidene)Bis(Pyridine)(Tricyclohexylphosphine)-, (Oc-6-13)- is a highly specialized organometallic complex, primarily recognized as a Grubbs-Hoveyda type second-generation catalyst precursor. This compound matters significantly for its role in enabling highly efficient and selective olefin metathesis reactions, a cornerstone technology in modern synthetic chemistry. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over carbon-carbon double bond formation to construct complex molecular architectures.
Application
- Ring-Closing Metathesis (RCM): Key for synthesizing medium and large cyclic compounds, including heterocycles, prevalent in natural product and active pharmaceutical ingredient (API) development.
- Cross Metathesis (CM): Used for the selective coupling of two different olefins to create new functionalized molecules for specialty chemicals and polymer precursors.
- Ring-Opening Metathesis Polymerization (ROMP): Employed in the production of specialized polymers with unique mechanical and chemical properties for advanced materials and coatings.
- Pharmaceutical Intermediate Synthesis: Facilitates the efficient construction of complex, stereodefined scaffolds crucial for drug discovery and development pipelines.
- Agrochemical Synthesis: Applied in creating novel active ingredients with specific stereochemistry for crop protection agents.
- Fine Chemical and Fragrance Manufacturing: Enables the synthesis of specific olefinic isomers and complex organic molecules where traditional methods are inefficient.
- Academic and Industrial R&D: Serves as a critical tool for methodology development and exploring new chemical spaces in catalysis.
Basic Information
| Item | Details |
|---|---|
| Product Name | Ruthenium, Dichloro(3-Phenyl-1H-Inden-1-Ylidene)Bis(Pyridine)(Tricyclohexylphosphine)-, (Oc-6-13)- |
| CAS No. | 920278-29-1 |
| Molecular Formula | C44H55Cl2N2PRu |
| Molecular Weight | 808.88 g/mol |
| Synonyms | Grubbs-Hoveyda II Catalyst; Hoveyda-Grubbs Catalyst 2nd Generation; Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](3-phenyl-1H-inden-1-ylidene)(tricyclohexylphosphine)ruthenium(II); (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(3-phenyl-1H-inden-1-ylidene)(tricyclohexylphosphine)ruthenium(II); HG II Catalyst; Ru-IndenyliDene Complex; Zhan Catalyst 1B; [RuCl2(Ind)(H2IMes)(PCy3)] |
| EINECS | Contact for details |
Quality Control
Every batch of our ruthenium metathesis catalyst is manufactured and tested under stringent conditions to ensure high catalytic activity and batch-to-batch consistency. Our quality assurance protocol includes comprehensive analytical characterization to confirm identity and purity. Certificates of Analysis (COA) detailing specifications such as NMR purity, elemental analysis, and catalytic activity benchmarks are provided and available upon request to support your quality and regulatory requirements.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C or as specified on the label. This compound is light-sensitive and easily oxidized; prolonged exposure to air, moisture, or ambient light can lead to decomposition and loss of catalytic activity. Handle and store in a dedicated, well-ventilated area.
Specification
| Item | Specification |
|---|---|
| Appearance | Purple to brown crystalline solid |
| Identification (NMR) | Conforms to structure |
| Purity (NMR) | ≥ 95% |
| Assay (Ru content) | Contact for details |
| Solubility | Soluble in common organic solvents (DCM, toluene, THF) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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