Description

9-Hydroxy-3-Aza-Spiro[5.5]Undecane-3-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and aza-heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation therapeutics.

Application

• Key Intermediate in API Synthesis: Serves as a crucial building block for the production of complex drug molecules, especially in central nervous system (CNS) and metabolic disease research pipelines.
• Medicinal Chemistry Research: Used extensively in drug discovery and lead optimization studies to explore new chemical entities and their biological activities.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot and commercial manufacturing scales.
• Pre-clinical and Clinical Trial Material Production: Supplied for the synthesis of compounds required for toxicology studies and clinical trial batches.
• Custom Synthesis Projects: A starting material for contract research and manufacturing organizations (CROs/CMOs) working on proprietary client molecules.

Basic Information

Product Name	9-Hydroxy-3-Aza-Spiro[5.5]Undecane-3-Carboxylic Acid tert-Butyl Ester
CAS No.	918644-73-2
Molecular Formula	C15H27NO3
Molecular Weight	269.38 g/mol
Synonyms	tert-Butyl 9-hydroxy-3-azaspiro[5.5]undecane-3-carboxylate; 3-Azaspiro[5.5]undecane-3-carboxylic acid, 9-hydroxy-, 1,1-dimethylethyl ester; 9-Hydroxy-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester; 3-Boc-9-hydroxy-3-azaspiro[5.5]undecane; 9-Hydroxy-3-azaspiro[5.5]undecane-3-carboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 9-Hydroxy-3-Aza-Spiro[5.5]Undecane-3-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and current Good Manufacturing Practice (cGMP) principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.