Description

3H-Pyrrolo[2,3-C]Quinoline-1-Carboxylic Acid, 4,5-Dihydro-4-Oxo-8-[(Phenylamino)Sulfonyl]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. Pharmaceutical companies, contract research organizations (CROs), and fine chemical manufacturers specializing in small molecule drug discovery and active pharmaceutical ingredient (API) development are the primary industrial users of this specialized chemical.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• Kinase Inhibitor Development: Its core scaffold is valuable for constructing molecules designed to modulate kinase activity, relevant in oncology and inflammatory disease research.
• Chemical Biology Probes: Utilized to create specialized tools for studying biological pathways and target validation in cellular assays.
• Custom Synthesis & Contract Manufacturing: Supplied to partners requiring this specific, high-value intermediate for proprietary synthesis projects.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3H-Pyrrolo[2,3-C]Quinoline-1-Carboxylic Acid, 4,5-Dihydro-4-Oxo-8-[(Phenylamino)Sulfonyl]-
CAS No.	918473-12-8
Molecular Formula	C18H13N3O5S
Molecular Weight	383.38 g/mol
Synonyms	8-[(Phenylamino)sulfonyl]-4,5-dihydro-4-oxo-3H-pyrrolo[2,3-c]quinoline-1-carboxylic acid; 1-Carboxy-4,5-dihydro-4-oxo-8-[(phenylamino)sulfonyl]-3H-pyrrolo[2,3-c]quinoline; 918473-12-8; Pyrroloquinoline sulfonamide derivative; 8-(Phenylsulfamoyl)-4,5-dihydro-4-oxo-1H-pyrrolo[2,3-c]quinoline-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research and development applications. All material is supplied with a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We implement in-process controls and final release testing according to ICH guidelines where applicable, supporting our commitment to supplying materials suitable for use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.