Description

1H-Pyrazole-4-Carboxylic Acid, 5-Amino-1-(2,4-Difluorophenyl)- is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and fine chemical production.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry research.
• API Development: Used in the research and scale-up production of Active Pharmaceutical Ingredients (APIs) targeting various disease pathways.
• Biochemical Research: Serves as a precursor or reference standard in biochemical assays and pharmacological studies.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecules for agrochemical or material science applications.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1H-Pyrazole-4-Carboxylic Acid, 5-Amino-1-(2,4-Difluorophenyl)-
CAS No.	918405-21-7
Molecular Formula	C10H7F2N3O2
Molecular Weight	239.18 g/mol
Synonyms	5-Amino-1-(2,4-difluorophenyl)-1H-pyrazole-4-carboxylic acid; 1-(2,4-Difluorophenyl)-5-amino-1H-pyrazole-4-carboxylic acid; 918405-21-7; 5-Amino-1-(2,4-difluorophenyl)pyrazole-4-carboxylic acid; 1H-Pyrazole-4-carboxylic acid, 5-amino-1-(2,4-difluorophenyl)-; 5-Amino-1-(2,4-difluorophenyl)-4-pyrazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazole-4-Carboxylic Acid, 5-Amino-1-(2,4-Difluorophenyl)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.