Description

1-Bromo-3-Methyl-5-(Methylsulfonyl)Benzene is a high-purity, multi-functional aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromine and methylsulfonyl substituents, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries for applications such as Suzuki cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammation.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogen and sulfone functionality.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed Suzuki, Stille, and other cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.
• Ligand and Catalyst Development: Used to synthesize novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-Bromo-3-Methyl-5-(Methylsulfonyl)Benzene
CAS No.	918350-17-1
Molecular Formula	C9H11BrO2S
Molecular Weight	263.15 g/mol
Synonyms	3-Bromo-5-methylphenyl methyl sulfone; 5-Bromo-3-methylphenyl methyl sulfone; 1-Bromo-3-methyl-5-(methylsulfonyl)benzene; 3-Methyl-5-(methylsulfonyl)bromobenzene; Methyl 3-bromo-5-methylphenyl sulfone; (3-Bromo-5-methylphenyl)(methyl)sulfone
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Methyl-5-(Methylsulfonyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.