Description

(R)-3-(4-Fluorophenyl)Pent-4-Enoic Acid is a high-purity chiral building block featuring a fluorinated aromatic ring and a terminal alkene functional group. This compound is of significant value in modern pharmaceutical and agrochemical research, serving as a versatile intermediate for the synthesis of more complex, biologically active molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the fluorine atom and chiral center can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: The alkene moiety allows for polymerization or functionalization, making it a candidate monomer for specialty polymers with unique optical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific compounds on scale.

Basic Information

Product Name	(R)-3-(4-Fluorophenyl)Pent-4-Enoic Acid
CAS No.	918149-75-4
Molecular Formula	C11H11FO2
Molecular Weight	194.20 g/mol
Synonyms	(R)-3-(p-Fluorophenyl)-4-pentenoic Acid; (R)-3-(4-Fluorophenyl)-4-pentenoic Acid; (3R)-3-(4-Fluorophenyl)pent-4-enoic Acid; (R)-3-(4-Fluorophenyl)pent-4-enoic Acid; (R)-3-(4-Fluorophenyl)-4-pentenoic Acid; (R)-3-(4-Fluorophenyl)pent-4-enoic Acid; (R)-3-(4-Fluorophenyl)-4-pentenoic Acid; (R)-3-(4-Fluorophenyl)pent-4-enoic Acid
EINECS	Contact for details

Quality Control

Our (R)-3-(4-Fluorophenyl)Pent-4-Enoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.