Description

Methyl 3-(2-Methoxyphenyl)-2,4-Dioxo-1,2,3,4-Tetrahydroquinazoline-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline-dione class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value chemical products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinazoline-based drug candidates, particularly for applications in oncology and central nervous system (CNS) disorders.
• Agrochemical Research: Serves as a structural scaffold for developing new herbicides, fungicides, and plant growth regulators with specific modes of action.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing complex heterocyclic frameworks due to its reactive carbonyl and ester functional groups.
• Biochemical Research: Employed in biochemical assays and as a tool compound for studying enzyme inhibition and biological pathways.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with unique thermal or optical properties.

Basic Information

Product Name	Methyl 3-(2-Methoxyphenyl)-2,4-Dioxo-1,2,3,4-Tetrahydroquinazoline-7-Carboxylate
CAS No.	917889-26-0
Molecular Formula	C₁₇H₁₄N₂O₅
Molecular Weight	326.30 g/mol
Synonyms	7-Carbomethoxy-3-(2-methoxyphenyl)-1,2,3,4-tetrahydro-2,4-quinazolinedione; Methyl 3-(o-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylate; 3-(2-Methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylic acid methyl ester; Quinazoline-7-carboxylic acid, 1,2,3,4-tetrahydro-3-(2-methoxyphenyl)-2,4-dioxo-, methyl ester; 917889-26-0; Methyl 3-(2-methoxyphenyl)-2,4-dioxo-3,4-dihydroquinazoline-7-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-(2-Methoxyphenyl)-2,4-Dioxo-1,2,3,4-Tetrahydroquinazoline-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.