Description

2-Chloro-6,8-Dimethylquinoline-3-Carbonitrile is a high-value, multi-functional quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated and nitrile-substituted structure makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the quinoline scaffold's bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological processes and enzyme inhibition.
• Catalyst Ligand Synthesis: Acts as a starting material for synthesizing sophisticated nitrogen-containing ligands used in asymmetric catalysis.
• Academic & Contract Research: A valuable reagent for methodology development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	2-Chloro-6,8-Dimethylquinoline-3-Carbonitrile
CAS No.	917750-50-6
Molecular Formula	C₁₂H₉ClN₂
Molecular Weight	216.67 g/mol
Synonyms	2-Chloro-6,8-dimethyl-3-quinolinecarbonitrile; 3-Cyano-2-chloro-6,8-dimethylquinoline; 6,8-Dimethyl-2-chloroquinoline-3-carbonitrile; Quinoline-3-carbonitrile, 2-chloro-6,8-dimethyl-; 2-Chloro-6,8-dimethylquinoline-3-carbonitrile; 917750-50-6 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Chloro-6,8-Dimethylquinoline-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and process chemistry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.