Description

8-Bromo-5-Fluoroquinoline is a high-purity, halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which enables the development of novel pharmacologically active molecules and functional materials. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for creating new compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in developing quinolone-based antibiotics, kinase inhibitors, and other therapeutic agents.
• Agrochemical Research: Used in the discovery and development of new pesticides and herbicides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a building block for creating organic ligands in catalysis, as well as for developing advanced organic electronic materials and fluorescent dyes.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex quinoline motifs into larger molecular architectures.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	8-Bromo-5-Fluoroquinoline
CAS No.	917251-99-1
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	8-Bromo-5-fluoroquinoline; 5-Fluoro-8-bromoquinoline; Quinoline, 8-bromo-5-fluoro-; 8-Br-5-F-quinoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Fluoroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.