Description

8-Chloro-5-Fluoro-4-Methoxy-2-(Trifluoromethyl)Quinoline is a high-value, multi-functionalized quinoline derivative that serves as a critical building block in advanced organic synthesis. Its complex halogenated and trifluoromethylated structure makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals with enhanced properties. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating next-generation compounds with improved efficacy and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research pipelines.
• Agrochemical Development: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups contribute to biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and charge-transport materials.
• Ligand and Catalyst Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorinated Compound Library: A valuable building block for creating diverse fluorinated compound libraries used in high-throughput screening for drug discovery.

Basic Information

Product Name	8-Chloro-5-Fluoro-4-Methoxy-2-(Trifluoromethyl)Quinoline
CAS No.	917251-95-7
Molecular Formula	C₁₁H₆ClF₄NO
Molecular Weight	279.62 g/mol
Synonyms	8-Chloro-5-fluoro-4-methoxy-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-8-chloro-5-fluoro-4-methoxyquinoline; Quinoline, 8-chloro-5-fluoro-4-methoxy-2-(trifluoromethyl)-; 917251-95-7; 8-Chloro-5-fluoro-4-methoxy-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Our production of 8-Chloro-5-Fluoro-4-Methoxy-2-(Trifluoromethyl)Quinoline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical-grade applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.