Description

8-Bromo-3-(trifluoromethyl)quinoline is a high-purity, halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which combines a bromine substituent for further functionalization with a robust trifluoromethyl group to modulate electronic properties and metabolic stability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, antiviral agents, and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the quinoline core and fluorine atoms contribute to efficacy and environmental persistence.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers, organic semiconductors, and liquid crystal materials.
• Chemical Synthesis: Acts as a versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions, enabling complex molecular architecture construction.
• Fluorescent Probe Development: The quinoline structure can be utilized as a core for developing fluorescent dyes and sensors for biological or chemical detection.

Basic Information

Product Name	8-Bromo-3-(trifluoromethyl)quinoline
CAS No.	917251-86-6
Molecular Formula	C10H5BrF3N
Molecular Weight	276.06 g/mol
Synonyms	8-Bromo-3-(trifluoromethyl)quinoline; Quinoline, 8-bromo-3-(trifluoromethyl)-; 3-(Trifluoromethyl)-8-bromoquinoline; 8-Bromo-3-trifluoromethylquinoline; 917251-86-6
EINECS	Contact for details

Quality Control

Our 8-Bromo-3-(trifluoromethyl)quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.