Description

8-Bromo-3-Iodoquinoline is a high-purity halogenated quinoline derivative, a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and iodine substituents, makes it an invaluable intermediate for constructing complex molecules, particularly in pharmaceutical research and material science. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in cross-coupling reactions, ligand synthesis, and the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting neurological disorders, infectious diseases, and oncology.
• Agrochemical Research: Used in the development of novel fungicides, herbicides, and insecticides, leveraging the quinoline scaffold's bioactivity.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), conductive polymers, and other advanced functional materials.
• Catalyst & Ligand Synthesis: Employed to create sophisticated ligands for transition metal catalysts used in fine chemical and asymmetric synthesis.
• Cross-Coupling Reactions: The bromine and iodine atoms provide distinct reactivity for sequential Suzuki, Stille, or Sonogashira cross-coupling reactions to build complex molecular architectures.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	8-Bromo-3-Iodoquinoline
CAS No.	917251-85-5
Molecular Formula	C9H5BrIN
Molecular Weight	333.95 g/mol
Synonyms	3-Iodo-8-bromoquinoline; Quinoline, 8-bromo-3-iodo-; 8-Bromo-3-iodoquinoline; 8-Brom-3-jodchinolin (German); 8-ブロモ-3-ヨードキノリン (Japanese)
EINECS	Contact for details

Quality Control

Our 8-Bromo-3-Iodoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to consistent quality and traceability supports your R&D and scale-up processes with reliable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.