Description

1-(7-Fluoro-8-Quinolinyl)-4-Piperidinone is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoline-piperidinone hybrid structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, particularly for targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting kinase inhibition.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Used in the development of novel heterocyclic compounds for agrochemical and material science applications.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme interactions and cellular signaling mechanisms.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	1-(7-Fluoro-8-Quinolinyl)-4-Piperidinone
CAS No.	917251-83-3
Molecular Formula	C14H13FN2O
Molecular Weight	244.27 g/mol
Synonyms	4-Piperidinone, 1-(7-fluoro-8-quinolinyl)-; 1-(7-Fluoroquinolin-8-yl)piperidin-4-one; 8-(4-Oxopiperidin-1-yl)-7-fluoroquinoline; 7-Fluoro-8-(4-oxopiperidin-1-yl)quinoline
EINECS	Contact for details

Quality Control

Our 1-(7-Fluoro-8-Quinolinyl)-4-Piperidinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.