Description

1H-Imidazole, 4-Methyl-1-[3-Nitro-5-(Trifluoromethyl)Phenyl]- is a specialized heterocyclic organic compound featuring a nitro and trifluoromethyl substituted phenyl ring attached to a methyl-imidazole core. This unique structure makes it a valuable and versatile building block (synthon) for advanced chemical synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in creating novel molecules with specific electronic and steric properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Ligand Synthesis: Employed in organometallic chemistry to create complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Utilized as a probe or tag in biochemical research due to its distinctive structural and potential fluorescent properties.
• Custom Synthesis & Contract Manufacturing: A critical raw material for custom synthesis houses producing high-value, low-volume specialty chemicals for client-specific projects.

Basic Information

Product Name	1H-Imidazole, 4-Methyl-1-[3-Nitro-5-(Trifluoromethyl)Phenyl]-
CAS No.	916975-92-3
Molecular Formula	C11H8F3N3O2
Molecular Weight	271.20 g/mol
Synonyms	4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole; 1-(3-Nitro-5-trifluoromethylphenyl)-4-methylimidazole; 4-Methyl-1-(3-nitro-5-(trifluoromethyl)phenyl)imidazole; 1H-Imidazole, 4-methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-; 916975-92-3; 4-Methyl-1-(3-nitro-5-trifluoromethylphenyl)imidazole
EINECS	Contact for details

Quality Control

Our production of 1H-Imidazole, 4-Methyl-1-[3-Nitro-5-(Trifluoromethyl)Phenyl]- adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.