Description

Ethyl 2-(2-(Methylamino)Pyrimidin-4-Yl)-1H-Indole-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and targeted therapy domains.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of kinase inhibitors and other targeted therapies.
• Biochemical Tool Compound: Used in vitro and in vivo to study specific biological pathways and validate novel drug targets.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Academic Research: Utilized in university and institutional labs for pioneering research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	Ethyl 2-(2-(Methylamino)Pyrimidin-4-Yl)-1H-Indole-5-Carboxylate
CAS No.	916486-06-1
Molecular Formula	C₁₆H₁₆N₄O₂
Molecular Weight	296.33 g/mol
Synonyms	Ethyl 2-[2-(Methylamino)pyrimidin-4-yl]-1H-indole-5-carboxylate; 5-Carbethoxy-2-[2-(methylamino)-4-pyrimidinyl]indole; 1H-Indole-5-carboxylic acid, 2-[2-(methylamino)-4-pyrimidinyl]-, ethyl ester; 2-(2-(Methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylic acid ethyl ester; Ethyl 2-(2-(methylamino)pyrimidin-4-yl)indole-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(2-(Methylamino)Pyrimidin-4-Yl)-1H-Indole-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.