Description

1-Benzylspiro[Indole-3,4''-Piperidin]-2(1H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic indole-piperidine structure. This compound is of significant value in medicinal chemistry research and development, serving as a critical building block for novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with spirocyclic architectures.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• CNS Drug Development: Employed in the research of potential therapeutics for neurological and psychiatric conditions, leveraging its privileged indole-piperidine structure.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for chemical biology studies and the development of new synthetic methodologies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-Benzylspiro[Indole-3,4''-Piperidin]-2(1H)-One
CAS No.	916445-11-9
Molecular Formula	C19H20N2O
Molecular Weight	292.38 g/mol
Synonyms	1-Benzylspiro[indole-3,4'-piperidin]-2(1H)-one; 1-Benzyl-1'H-spiro[indole-3,4'-piperidin]-2-one; 1-Benzylspiro[indoline-3,4'-piperidin]-2-one; 916445-11-9; Spiro[indole-3,4'-piperidine]-2-one, 1-benzyl-; 1-Benzyl-1,2-dihydrospiro[indole-3,4'-piperidin]-2-one; 1-Benzyl-2-oxospiro[indoline-3,4'-piperidine]; 1-Benzyl-2-oxo-1,2-dihydrospiro[indole-3,4'-piperidine]
EINECS	Contact for details

Quality Control

Our 1-Benzylspiro[Indole-3,4''-Piperidin]-2(1H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates, and specifications can be aligned with client requirements for specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.