Description

3-(4-Fluorophenyl)-4,5,6,7-Tetrahydro-2H-Pyrazolo[4,3-C]Pyridine CAS NO 916423-52-4 is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyridine class of heterocyclic compounds. This compound is a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical and biotechnology sectors seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, especially for neurological and psychiatric applications.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold for constructing complex molecules with potential therapeutic activity.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies within R&D facilities.
• Preclinical & Clinical Trial Material: Supplied under controlled conditions for the production of materials required for regulatory studies.
• Contract Manufacturing (CMO): A critical raw material for contract development and manufacturing organizations serving the global pharmaceutical market.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	3-(4-Fluorophenyl)-4,5,6,7-Tetrahydro-2H-Pyrazolo[4,3-C]Pyridine
CAS No.	916423-52-4
Molecular Formula	C12H12FN3
Molecular Weight	217.24 g/mol
Synonyms	3-(4-Fluorophenyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine; 4,5,6,7-Tetrahydro-3-(4-fluorophenyl)-2H-pyrazolo[4,3-c]pyridine; 3-(p-Fluorophenyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine; Pyrazolo[4,3-c]pyridine, 3-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-; 916423-52-4; FC-1012 (Potential R&D Code); 3-(4-Fluorophenyl)-2,4,5,6,7,8-hexahydropyrazolo[4,3-c]pyridine
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-4,5,6,7-Tetrahydro-2H-Pyrazolo[4,3-C]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant regulatory guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.