Description

3-(Carboxymethyl)-5-Methoxybenzotrifluoride, also known as 3-(Carboxymethyl)-5-(Trifluoromethyl)Anisole, is a high-value trifluoromethylated aromatic building block. This compound is critical for synthesizing advanced molecules where the introduction of both a carboxylic acid derivative and a trifluoromethyl group is required. It is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas like oncology, CNS, and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves bioavailability and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for specialty chemicals used in electronic displays and organic light-emitting diodes.
• Advanced Polymer Modifier: Incorporated into polymer chains to impart specific chemical resistance, thermal stability, or surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis and scale-up projects.
• Fluorinated Surfactant Research: Acts as a precursor in the development of novel fluorosurfactants with unique surface activity.

Basic Information

Product Name	3-(Carboxymethyl)-5-Methoxybenzotrifluoride
CAS No.	916421-04-0
Molecular Formula	C10H9F3O3
Molecular Weight	234.17 g/mol
Synonyms	3-(Carboxymethyl)-5-(Trifluoromethyl)Anisole; 5-Methoxy-3-(trifluoromethyl)benzoic Acid, Methyl Ester (misnomer check required); 2-Methoxy-5-(methoxycarbonyl)benzotrifluoride; Methyl 5-Methoxy-3-(trifluoromethyl)benzoate; 3-(Methoxycarbonyl)-5-(trifluoromethyl)anisole; 916421-04-0; α-Methoxycarbonyl-3-methoxy-5-trifluoromethylbenzene
EINECS	Contact for details

Quality Control

Our 3-(Carboxymethyl)-5-Methoxybenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For custom synthesis projects, we adhere to cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.