Description

3-[4-Chloro-2-(Trifluoromethyl)Phenyl]Propionic Acid is a high-value fluorinated aromatic carboxylic acid building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique trifluoromethyl and chloro substituents impart desirable biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in anti-inflammatory and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers and compounds used in electronic display technologies.
• Organic Synthesis Reagent: A versatile reagent for coupling reactions and as a precursor for esters, amides, and other derivatives in fine chemical production.
• Chemical Research & Development: Essential for academic and industrial R&D exploring new fluorinated compounds and their properties.

Basic Information

Product Name	3-[4-Chloro-2-(Trifluoromethyl)Phenyl]Propionic Acid
CAS No.	916420-46-7
Molecular Formula	C10H8ClF3O2
Molecular Weight	252.62 g/mol
Synonyms	4-Chloro-2-(trifluoromethyl)hydrocinnamic Acid; 3-(4-Chloro-2-(trifluoromethyl)phenyl)propanoic Acid; 2-(Trifluoromethyl)-4-chlorohydrocinnamic Acid; 3-(4-Chloro-alpha,alpha,α-trifluoro-o-tolyl)propionic Acid; 916420-46-7; 3-(4-Chloro-2-trifluoromethylphenyl)propionic Acid
EINECS	Contact for details

Quality Control

Our production of 3-[4-Chloro-2-(Trifluoromethyl)Phenyl]Propionic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards required for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability, although the product is stable at controlled room temperature for shorter periods. The container must be kept tightly sealed due to the compound's sensitivity to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.