Description

3-[5-Fluoro-2-(Trifluoromethyl)Phenyl]Propionic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens, improving the dielectric anisotropy and stability of display components.
• Organic Electronics: Employed in the synthesis of semiconducting polymers and small molecules for OLEDs and OFETs, where fluorination improves electron mobility and device efficiency.
• Advanced Material Research: Acts as a versatile building block for creating specialty polymers and coatings with enhanced chemical resistance and surface properties.

Basic Information

Product Name	3-[5-Fluoro-2-(Trifluoromethyl)Phenyl]Propionic Acid
CAS No.	916420-43-4
Molecular Formula	C10H6F4O2
Molecular Weight	234.15 g/mol
Synonyms	5-Fluoro-α,α,α-trifluoro-o-tolylpropionic Acid; 3-(5-Fluoro-2-(trifluoromethyl)phenyl)propanoic Acid; 2-(Trifluoromethyl)-5-fluorophenylpropionic Acid; 916420-43-4; 3-(5-Fluoro-2-trifluoromethylphenyl)propionic Acid; β-(5-Fluoro-2-(trifluoromethyl)phenyl)propionic Acid
EINECS	Contact for details

Quality Control

Our production of 3-[5-Fluoro-2-(Trifluoromethyl)Phenyl]Propionic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up processes. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.